Review
doi: 10.1016/s0167-4781(98)00124-9.
Structure of DNA topoisomerases
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- PMID: 9748476
- DOI: 10.1016/s0167-4781(98)00124-9
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Review
Structure of DNA topoisomerases
Biochim Biophys Acta.
.
Abstract
Over the last several years topoisomerases have finally begun to yield to high-resolution structural studies. These models have greatly aided our understanding of the mechanisms of topoisomerase catalysis and drug interactions. This review will cover advances in the structural biology of topoisomerases and discuss their implications for topoisomerase function.
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