Transcription: gene control by targeted histone acetylation
- PMID: 9637914
- DOI: 10.1016/s0960-9822(98)70268-4
Transcription: gene control by targeted histone acetylation
Abstract
A transcriptional regulator in yeast, Gcn5p, activates transcription by targeted acetylation of specific lysine residues in the amino-terminal tails of histones. This targeted modification is restricted to nucleosomes assembled on the promoters of Gcn5p-responsive genes.
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