Review
doi: 10.1159/000014538.
Lipid modifications and membrane targeting of G alpha
Affiliations
- PMID: 9629464
- DOI: 10.1159/000014538
Item in Clipboard
Review
Lipid modifications and membrane targeting of G alpha
Biol Signals Recept.
1998 Mar-Apr.
Abstract
G protein alpha-subunits (G alpha) undergo palmitoylation and/or myristoylation. This review will focus on new insights into the function and regulation of these fatty acid modifications of G alpha. Most importantly, I will examine lipid modifications of G alpha in the context of a two-signal model for membrane attachment, discuss recent advances in the identification of palmitoyl transferases, and highlight several controversial issues in this field.
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