Review
doi: 10.1016/s0966-842x(98)01255-4.
Immune evasion by cytomegalovirus--survival strategies of a highly adapted opportunist
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- PMID: 9614343
- DOI: 10.1016/s0966-842x(98)01255-4
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Review
Immune evasion by cytomegalovirus--survival strategies of a highly adapted opportunist
Trends Microbiol.
1998 May.
Abstract
Slowly replicating, species-specific and complex DNA viruses, such as cytomegaloviruses (CMVs), which code for > 200 antigenic proteins, should be easy prey to the host's immune system. Yet, CMVs are amazingly adapted opportunists that cope with multiple immune responses. Frequently, CMVs exploit immune mechanisms generated by the host. These strategies secure the persistence of CMVs and provide opportunities to spread to naive individuals.
Comment in
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Cytomegaloviruses: their drive to achieve permanent coexistence with their hosts.Trends Microbiol. 1998 Jul;6(7):260. doi: 10.1016/s0966-842x(98)01297-9. Trends Microbiol. 1998. PMID: 9717213 No abstract available.
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