Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1998 May;43(5):988-92.
doi: 10.1023/a:1018870415898.

Prevalence of upper gastrointestinal lesions and Helicobacter pylori infection in Crohn's disease

R D'Incà  1 , G Sturniolo, M Cassaro, C di Pace, G Longo, I Callegari, M Rugge
Affiliations

Prevalence of upper gastrointestinal lesions and Helicobacter pylori infection in Crohn's disease

R D'Incà et al. Dig Dis Sci. 1998 May.

Abstract

Crohn's disease can affect the upper gut with reported variable frequency, although concurrent Helicobacter pylori infection has been reported to be low. We prospectively investigated the prevalence of esophageal, gastric, and duodenal lesions and Helicobacter pylori infection in 67 Crohn's disease, 41 ulcerative colitis patients, and 43 controls. Symptoms, esophagogastroduodenoscopy, and multiple biopsies were performed on all patients consecutively. Endoscopic lesions were found in 63% of Crohn's disease patients, with a Helicobacter pylori prevalence of 28%. Granulomas were found in three patients. Twenty-two percent of the ulcerative colitis patients had lesions, with a 29% prevalence of Helicobacter pylori infection. Half of the controls had pathological endoscopy, and Helicobacter pylori was positive in 40% of the cases. Subjective symptoms did not predict the presence of endoscopic lesions or Helicobacter pylori infection in inflammatory bowel disease patients. Chronic gastritis and duodenitis are common in Crohn's disease patients, and the majority are not associated with Helicobacter pylori infection.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Gut. 1977 Feb;18(2):115-20 - PubMed
    1. J Pediatr Gastroenterol Nutr. 1989 May;8(4):442-6 - PubMed
    1. J Gastroenterol Hepatol. 1991 May-Jun;6(3):223-34 - PubMed
    1. Endoscopy. 1980 Nov;12 (6):288-94 - PubMed
    1. Am J Gastroenterol. 1981 Aug;76(2):103-9 - PubMed

LinkOut - more resources