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Review
. 1998 Jan;12(1):1-3.
doi: 10.1038/sj.leu.2400886.

Pre-progenitor cells: a proposed new category of hematopoietic precursor cells

Review

Pre-progenitor cells: a proposed new category of hematopoietic precursor cells

D Metcalf. Leukemia. 1998 Jan.

Abstract

Hematopoietic precursor cells capable of forming blast colonies in vitro appear to be a distinct transit population between stem cells and lineage-committed progenitor cells because the cells in such blast colonies are mainly lineage-committed progenitor cells. It is proposed that blast colony-forming cells be termed pre-progenitor cells (PPC) to encourage efforts to establish their biology and potential for initiating some types of leukemic populations more clearly.

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