Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1995;33(2):77-83.

Morphological study of microglia in human mesencephalon during the development and aging

T Wierzba-Bobrowicz  1 , E Gwiazda, Z Poszwińska
Affiliations
  • PMID: 8705275
Review

Morphological study of microglia in human mesencephalon during the development and aging

T Wierzba-Bobrowicz et al. Folia Neuropathol. 1995.

Abstract

To assess the cytogenesis and the structure of the microglial cells, we studied mesencephalons in 47 human fetuses at 7th-40th week of gestational age, and in 18 adult brains from 20 to 70 years. The microglial cells were identified and characterized by morphological criteria using immunohistochemical and histochemical techniques. As early as in the 8th week of gestational age RCA-1 positive cells were detected, mainly in form of amoeboid microglial cells. These microglial cells were observed around the germinal matrix, and at or near the wall of blood vessels. RCA-1 positive cells which were detected within leptomeninges were large but without processes. At the 16th-40th week of gestational age we observed in mesencephalon, amoeboid microglial cells, and also RCA-1 positive and ferritin reactive ramified microglial cells.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

LinkOut - more resources