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. 1993 May 6;363(6424):15-6.

doi: 10.1038/363015a0.

Signal transduction. How receptors turn Ras on

PMID: 8479530
DOI: 10.1038/363015a0

Comment

Signal transduction. How receptors turn Ras on

F McCormick. Nature. 1993.

. 1993 May 6;363(6424):15-6.

doi: 10.1038/363015a0.

Author

PMID: 8479530
DOI: 10.1038/363015a0

No abstract available

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Comment on

Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras.
Gale NW, Kaplan S, Lowenstein EJ, Schlessinger J, Bar-Sagi D. Gale NW, et al. Nature. 1993 May 6;363(6424):88-92. doi: 10.1038/363088a0. Nature. 1993. PMID: 8386805
Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation.
Egan SE, Giddings BW, Brooks MW, Buday L, Sizeland AM, Weinberg RA. Egan SE, et al. Nature. 1993 May 6;363(6424):45-51. doi: 10.1038/363045a0. Nature. 1993. PMID: 8479536
The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1.
Rozakis-Adcock M, Fernley R, Wade J, Pawson T, Bowtell D. Rozakis-Adcock M, et al. Nature. 1993 May 6;363(6424):83-5. doi: 10.1038/363083a0. Nature. 1993. PMID: 8479540
Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling.
Li N, Batzer A, Daly R, Yajnik V, Skolnik E, Chardin P, Bar-Sagi D, Margolis B, Schlessinger J. Li N, et al. Nature. 1993 May 6;363(6424):85-8. doi: 10.1038/363085a0. Nature. 1993. PMID: 8479541

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