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. 1977 Jan;41(1):122-6.

Binding effects of concanavalin A on a coronavirus

Binding effects of concanavalin A on a coronavirus

A S Greig et al. Can J Comp Med. 1977 Jan.

Abstract

Concanavalin A, a phytagglutinin, binds to the envelope of hemagglutinating encephalomyelitis virus, a Coronavirus. Concanavalin A treated virus suspensions lose their hemagglutination properties and there is a transient interference with infectivity. Electron micrographs show the Concanavalin A as a granular deposit adhering to the viral envelope and there is aggregation of the virus. Concanavalin A does not bind to virions stripped of their envelopes.

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