mtDNA and Y-chromosome polymorphisms in four Native American populations from southern Mexico
- PMID: 8304347
- PMCID: PMC1918164
mtDNA and Y-chromosome polymorphisms in four Native American populations from southern Mexico
Abstract
mtDNA sequence variation was examined in 60 Native Americans (Mixtecs from the Alta, Mixtecs from the Baja, Valley Zapotecs, and Highland Mixe) from southern Mexico by PCR amplification and high-resolution restriction endonuclease analysis. Four groups of mtDNA haplotypes (haplogroups A, B, C, and D) characterize Amerind populations, but only three (haplogroups A, B, and C) were observed in these Mexican populations. The comparison of their mtDNA variation with that observed in other populations from Mexico and Central America permits a clear distinction among the different Middle American tribes and raises questions about some of their linguistic affiliations. The males of these population samples were also analyzed for Y-chromosome RFLPs with the probes 49a, 49f, and 12f2. This analysis suggests that certain Y-chromosome haplotypes were brought from Asia during the colonization of the Americas, and a differential gene flow was introduced into Native American populations from European males and females.
Comment in
-
MtDNA haplogroups in Native Americans.Am J Hum Genet. 1995 May;56(5):1234-8. Am J Hum Genet. 1995. PMID: 7726181 Free PMC article. No abstract available.
Similar articles
-
The dual origin and Siberian affinities of Native American Y chromosomes.Am J Hum Genet. 2002 Jan;70(1):192-206. doi: 10.1086/338457. Epub 2001 Nov 30. Am J Hum Genet. 2002. PMID: 11731934 Free PMC article.
-
Asian affinities and continental radiation of the four founding Native American mtDNAs.Am J Hum Genet. 1993 Sep;53(3):563-90. Am J Hum Genet. 1993. PMID: 7688932 Free PMC article.
-
Mitochondrial DNA and Y chromosome-specific polymorphisms in the Seminole Tribe of Florida.Eur J Hum Genet. 1997 Jan-Feb;5(1):25-34. Eur J Hum Genet. 1997. PMID: 9156318
-
MtDNA and Y chromosome polymorphisms in Hungary: inferences from the palaeolithic, neolithic and Uralic influences on the modern Hungarian gene pool.Eur J Hum Genet. 2000 May;8(5):339-46. doi: 10.1038/sj.ejhg.5200468. Eur J Hum Genet. 2000. PMID: 10854093
-
Distribution of four founding mtDNA haplogroups among Native North Americans.Am J Phys Anthropol. 1996 Nov;101(3):307-23. doi: 10.1002/(SICI)1096-8644(199611)101:3<307::AID-AJPA1>3.0.CO;2-W. Am J Phys Anthropol. 1996. PMID: 8922178 Review.
Cited by
-
Evaluating the Farming/Language Dispersal Hypothesis with genetic variation exhibited by populations in the Southwest and Mesoamerica.Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6759-64. doi: 10.1073/pnas.0905753107. Epub 2010 Mar 29. Proc Natl Acad Sci U S A. 2010. PMID: 20351276 Free PMC article.
-
Genetic differences between Chibcha and Non-Chibcha speaking tribes based on mitochondrial DNA (mtDNA) haplogroups from 21 Amerindian tribes from Colombia.Genet Mol Biol. 2013 Jul;36(2):149-57. doi: 10.1590/S1415-47572013005000011. Epub 2013 Mar 5. Genet Mol Biol. 2013. PMID: 23885195 Free PMC article.
-
The dual origin and Siberian affinities of Native American Y chromosomes.Am J Hum Genet. 2002 Jan;70(1):192-206. doi: 10.1086/338457. Epub 2001 Nov 30. Am J Hum Genet. 2002. PMID: 11731934 Free PMC article.
-
A view of the neolithic demic diffusion in Europe through two Y chromosome-specific markers.Am J Hum Genet. 1996 Oct;59(4):964-8. Am J Hum Genet. 1996. PMID: 8808616 Free PMC article. No abstract available.
-
Mutation patterns of mtDNA: empirical inferences for the coding region.BMC Evol Biol. 2008 Jun 2;8:167. doi: 10.1186/1471-2148-8-167. BMC Evol Biol. 2008. PMID: 18518963 Free PMC article.
References
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources