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Comparative Study
. 1993 Jan 30;341(8840):271-3.
doi: 10.1016/0140-6736(93)92617-3.

Mycoplasma fermentans in individuals seropositive and seronegative for HIV-1

V L Katseni  1 , C B Gilroy, B K Ryait, K Ariyoshi, P D Bieniasz, J N Weber, D Taylor-Robinson
Affiliations
Comparative Study

Mycoplasma fermentans in individuals seropositive and seronegative for HIV-1

V L Katseni et al. Lancet. .

Abstract

Mycoplasmas have been suggested as a co-factor to explain various puzzling features of infection by human immunodeficiency virus 1 (HIV-1). We sought Mycoplasma fermentans by means of a semi-nested polymerase chain reaction (PCR) in samples of peripheral-blood mononuclear cells (PBMC), throat swabs, and urine samples from 117 HIV-seropositive patients (of whom 114 were homosexual men). M fermentans was detected in 12 (10%) PBMC samples, 15 (23%) of 65 throat samples, and 4 (8%) of 55 urine samples from the seropositive subjects. The organism was detected in similar proportions among 73 HIV-seronegative patients recruited from a sexually transmitted diseases clinic (9%, 20%, and 6%, respectively); again, most of the men (40 of 50) in this group were homosexual. We found no association between infection by the mycoplasma and stage of disease, CD4 count, or HIV-1 load. These findings do not, however, eliminate the possibility that the mycoplasmal infection could affect the speed of disease progression.

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  • Mycoplasmas in HIV-1 seropositive patients.
    Bebear C, de Barbeyrac B, Clerc MT, Renaudin H, Fleury HJ, Dupon M, Ragnaud JM, Morlat P. Bebear C, et al. Lancet. 1993 Mar 20;341(8847):758-9. doi: 10.1016/0140-6736(93)90531-k. Lancet. 1993. PMID: 8095655 No abstract available.

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