Breast cancer in sub-Saharan African women
- PMID: 7839882
Breast cancer in sub-Saharan African women
Abstract
The literature on breast cancer in sub-Saharan women is reviewed. In general, breast cancer is the second most common malignancy of women in the region, after cancer of the uterine cervix. Available reports indicate that data on the disease are incomplete and mostly, of epidemiological or clinical nature. Breast cancer is less common in sub-Saharan Africa compared to the Western countries (USA or Europe), occurs in younger individuals with peak incidences about a decade younger and the majority present late, with advanced, sometimes terminal disease. Absence of health educational programmes on cancer as well as lack of screening facilities in nearly all countries in the region are contributory factors to the late presentation of the cases. The need for more in-depth studies of the disease in the black African population has been highlighted.
PIP: Although epidemiologic studies of breast cancer in sub-Saharan Africa are not available, the disease is considered the second most prevalent cancer among Black women in the region (exceeded only by cervical cancer). In Africa, as in the rest of the world, infiltrating duct carcinoma is the most common histologic type. Observed has been a trend toward relatively young age at diagnosis and presentation at late stages of disease progression. Early age at first birth and breast feeding--associated with a reduced risk of breast cancer in white women--do not appear to exert a protective effect among African women. Contributing to the late presentation of breast cancer cases is the lack of educational programs on breast self-examination and screening technologies such as mammography. Also unavailable are standard methods of treatment such as radiation, chemotherapy, and hormone receptor assay. The prognosis for women with breast cancer in sub-Saharan Africa is quite poor due to the advanced stage of most cases, poor patient compliance, the lack of treatment options, poor drug supplies, inadequate transportation, and a shortage of trained personnel.
Similar articles
-
Attitudes of Colorado health professionals toward breast and cervical cancer screening in Hispanic women.J Natl Cancer Inst Monogr. 1995;(18):95-100. J Natl Cancer Inst Monogr. 1995. PMID: 8562228
-
Breast cancer and conservative surgery in sub Saharan Africa.East Afr Med J. 1996 Feb;73(2):83-7. East Afr Med J. 1996. PMID: 8756044
-
Cervical cancer: the sub-Saharan African perspective.Reprod Health Matters. 2008 Nov;16(32):41-9. doi: 10.1016/S0968-8080(08)32415-X. Reprod Health Matters. 2008. PMID: 19027621 Review.
-
Breast cancer and human immunodeficiency virus infection: issues for the 21st century.J Womens Health (Larchmt). 2003 Apr;12(3):227-32. doi: 10.1089/154099903321667564. J Womens Health (Larchmt). 2003. PMID: 12804353 Review.
-
Prophylactic Oophorectomy: Reducing the U.S. Death Rate from Epithelial Ovarian Cancer. A Continuing Debate.Oncologist. 1996;1(5):326-330. Oncologist. 1996. PMID: 10388011
Cited by
-
Breast cancer screening pathways in Ghana: applying an exploratory single case study methodology with cross-case analysis.Heliyon. 2022 Nov 8;8(11):e11413. doi: 10.1016/j.heliyon.2022.e11413. eCollection 2022 Nov. Heliyon. 2022. PMID: 36387552 Free PMC article.
-
Knowledge, Attitude, and Practice (KAP) toward Cervical Cancer Screening among Adama Science and Technology University Female Students, Ethiopia.Int J Breast Cancer. 2022 Jan 13;2022:2490327. doi: 10.1155/2022/2490327. eCollection 2022. Int J Breast Cancer. 2022. PMID: 35070454 Free PMC article.
-
Breast cancer in sub-Saharan Africa: The current state and uncertain future.Exp Biol Med (Maywood). 2021 Jun;246(12):1377-1387. doi: 10.1177/15353702211006047. Epub 2021 Apr 29. Exp Biol Med (Maywood). 2021. PMID: 33926257 Free PMC article. Review.
-
Ethanolic extract of Nymphaea lotus L. (Nymphaeaceae) leaves exhibits in vitro antioxidant, in vivo anti-inflammatory and cytotoxic activities on Jurkat and MCF-7 cancer cell lines.BMC Complement Med Ther. 2021 Jan 7;21(1):22. doi: 10.1186/s12906-020-03195-w. BMC Complement Med Ther. 2021. PMID: 33413340 Free PMC article.
-
Novel BRCA2 pathogenic variant c.5219 T > G; p.(Leu1740Ter) in a consanguineous Senegalese family with hereditary breast cancer.BMC Med Genet. 2019 May 6;20(1):73. doi: 10.1186/s12881-019-0814-y. BMC Med Genet. 2019. PMID: 31060517 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Medical