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Review
. 1994 Aug;106(2):640-2.
doi: 10.1378/chest.106.2.640.

Bronchogenic carcinoma in patients seropositive for human immunodeficiency virus

S D Aaron  1 , E Warner, J D Edelson
Affiliations
Review

Bronchogenic carcinoma in patients seropositive for human immunodeficiency virus

S D Aaron et al. Chest. 1994 Aug.

Abstract

The purpose of this report is to describe an association between bronchogenic carcinoma and HIV. Three HIV-seropositive patients are described who developed bronchogenic cancer (two large cell, one adenocarcinoma) before developing an AIDS-defining illness. A critical review of the literature revealed 22 other patients in which the association of HIV infection and lung cancer is reported. These patients are characterized by a relatively young age at diagnosis (median, 43 years) and prevalence of the adenocarcinoma subtype (13 of 25 patients). Twenty of 21 patients had a history of smoking. Among 21 patients for whom data were available, 6 patients (28 percent) had AIDS at time of diagnosis of lung cancer while 11 patients (55 percent) did not have AIDS or AIDS-related complex at diagnosis.

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