Review
doi: 10.1016/0955-0674(95)80043-3.
Centrin, centrosomes, and mitotic spindle poles
Affiliations
- PMID: 7755988
- DOI: 10.1016/0955-0674(95)80043-3
Item in Clipboard
Review
Centrin, centrosomes, and mitotic spindle poles
Curr Opin Cell Biol.
1995 Feb.
Abstract
Centrin is a ubiquitous protein component of centrosomes and mitotic spindle poles. cDNA clones encoding centrin have been identified from vertebrate sources, and their sequences demonstrate that centrin is a highly conserved member of the EF-hand superfamily of calcium-binding proteins. Analysis of yeast and Chlamydomonas centrin mutants and experimental studies suggest that centrin has an essential role in the duplication of the centrosomes during the cell cycle, and in microtubule severing.
Similar articles
-
Cloning of a cDNA encoding human centrin, an EF-hand protein of centrosomes and mitotic spindle poles.J Cell Sci. 1994 Jan;107 ( Pt 1):9-16. doi: 10.1242/jcs.107.1.9. J Cell Sci. 1994. PMID: 8175926
-
Phosphorylation of centrin during the cell cycle and its role in centriole separation preceding centrosome duplication.J Biol Chem. 2001 Jun 8;276(23):20774-80. doi: 10.1074/jbc.M101324200. Epub 2001 Mar 12. J Biol Chem. 2001. PMID: 11279195
-
Function of donor cell centrosome in intraspecies and interspecies nuclear transfer embryos.Exp Cell Res. 2005 May 15;306(1):35-46. doi: 10.1016/j.yexcr.2005.02.009. Epub 2005 Mar 17. Exp Cell Res. 2005. PMID: 15878330
-
The role of mitotic kinases in coupling the centrosome cycle with the assembly of the mitotic spindle.J Cell Sci. 2014 Oct 1;127(Pt 19):4111-22. doi: 10.1242/jcs.151753. Epub 2014 Aug 15. J Cell Sci. 2014. PMID: 25128564 Review.
-
A mechanistic view on the evolutionary origin for centrin-based control of centriole duplication.J Cell Physiol. 2007 Nov;213(2):420-8. doi: 10.1002/jcp.21226. J Cell Physiol. 2007. PMID: 17694534 Review.
Cited by
-
Hydrogen/Deuterium Exchange Reflects Binding of Human Centrin 2 to Ca(2+) and Xeroderma Pigmentosum Group C Peptide: An Example of EX1 Kinetics.Int J Mass Spectrom. 2012 Dec 15;330-332:302-309. doi: 10.1016/j.ijms.2012.10.013. Epub 2012 Oct 27. Int J Mass Spectrom. 2012. PMID: 23439742 Free PMC article.
-
Cell division in Apicomplexan parasites is organized by a homolog of the striated rootlet fiber of algal flagella.PLoS Biol. 2012;10(12):e1001444. doi: 10.1371/journal.pbio.1001444. Epub 2012 Dec 11. PLoS Biol. 2012. PMID: 23239939 Free PMC article.
-
Transcriptional control of BubR1 by p53 and suppression of centrosome amplification by BubR1.Mol Cell Biol. 2005 May;25(10):4046-61. doi: 10.1128/MCB.25.10.4046-4061.2005. Mol Cell Biol. 2005. PMID: 15870277 Free PMC article.
-
Basal body duplication and maintenance require one member of the Tetrahymena thermophila centrin gene family.Mol Biol Cell. 2005 Aug;16(8):3606-19. doi: 10.1091/mbc.e04-10-0919. Epub 2005 Jun 8. Mol Biol Cell. 2005. PMID: 15944224 Free PMC article.
-
Cloning, localization, and axonemal function of Tetrahymena centrin.Mol Biol Cell. 2003 Jan;14(1):251-61. doi: 10.1091/mbc.e02-05-0298. Mol Biol Cell. 2003. PMID: 12529441 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases
