doi: 10.1093/genetics/82.4.639.
Mutants of Saccharomyces cerevisiae resistant to the alpha mating-type factor
- PMID: 773748
- PMCID: PMC1213485
- DOI: 10.1093/genetics/82.4.639
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Mutants of Saccharomyces cerevisiae resistant to the alpha mating-type factor
Genetics.
1976 Apr.
Abstract
Mutants that are resistant to alpha-factor have been isolated from a mating-type haploid strains of yeast by direct selection on agar medium containing partially purified alpha-factor. All resistant mutants isolated were found to be sterile. They were characterized and compared with mutants previously isolated as non-mating. Among 93 able to mate at low frequency and to sporulate, none showed linkage to the mating-type locus. The results support the hypothesis that the response to alpha-factor by cells of mating-type a is essential for mating.
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