doi: 10.1016/s0006-291x(83)80020-5.
Amino acid sequence of rat liver thiol proteinase inhibitor
- PMID: 6626228
- DOI: 10.1016/s0006-291x(83)80020-5
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Amino acid sequence of rat liver thiol proteinase inhibitor
Biochem Biophys Res Commun.
.
Abstract
The complete amino acid sequence of rat liver thiol proteinase inhibitor is presented. Its unique 98 residue sequence was derived mostly from analyses of a limited proteolysis product generated during the isolation of the protein with an active papain affinity column and of fragments produced by cleavage at arginyl bonds. The intact protein prepared with a tetrathionate inactivated ficin column has a unique amino-terminal sequence (Ac-Met-Met-Cys-). The inhibitor has no sequence homology with any proteinase inhibitor of known structure.
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