[Use of methods of 2-dimensional electrophoresis in population genetics]
- PMID: 6406297
[Use of methods of 2-dimensional electrophoresis in population genetics]
Abstract
The review of literature on application of the methods of two-dimensional electrophoresis according to O'Farrel, in population genetics and in some adjacent fields of biology, is presented. Resolution capacities of both conventional and two-dimensional electrophoresis are briefly characterized. Data on application of two-dimensional electrophoresis methods for evaluation the degree of inter- and intraspecific variability, for detection and characterization of mutations, as well as for analysis of molecular mechanisms of inborn pathology are reviewed.
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