doi: 10.1038/310025a0.
Sequence of a Drosophila segmentation gene: protein structure homology with DNA-binding proteins
- PMID: 6330566
- DOI: 10.1038/310025a0
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Sequence of a Drosophila segmentation gene: protein structure homology with DNA-binding proteins
Nature.
1984 Jul.
Abstract
Mutations in the fushi tarazu (ftz) locus of Drosophila result in embryos with half the usual number of body segments. The sequences of the wild-type gene, a temperature-sensitive allele and a dominant mutant allele are presented. A portion of the conserved protein domain present in ftz and several homoeotic genes resembles the DNA-binding region of prokaryotic DNA-binding proteins, and is also similar to products of the yeast mating-type locus.
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