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. 1981;70(4):321-9.
doi: 10.1007/BF01320247.

O-glycosidic carbohydrate-peptide linkages of Herpes simplex virus glycoproteins

S Olofsson, J Blomberg, E Lycke

O-glycosidic carbohydrate-peptide linkages of Herpes simplex virus glycoproteins

S Olofsson et al. Arch Virol. 1981.

Abstract

Electrophoretically purified HSV-specified glycoproteins with radiolabelled carbohydrates were subjected to mild alkaline borohydride treatment (0.5 M NaOH and 0.5 M NaBH4). The treatment liberated significant amounts of the labelled oligosaccharides. The latter demonstrated molecular weights of about 3,000 as determined by gel filtration. The glycoproteins involved probably belong to the gA/gB complex or gC. The results suggest that HSV specified glycoproteins contain oligosaccharides linked with an O-glycosidic bond to a threonine or serine residue of the polypeptide.

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