Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1984 Oct;3(10):2217-25.
doi: 10.1002/j.1460-2075.1984.tb02119.x.

Recycling of transferrin receptors in A431 cells is inhibited during mitosis

G Warren, J Davoust, A Cockcroft

Recycling of transferrin receptors in A431 cells is inhibited during mitosis

G Warren et al. EMBO J. 1984 Oct.

Abstract

There is a marked reduction in the number of surface transferrin receptors as A431 cells enter mitosis which persists until telophase when receptors reappear to a level that exceeds the original interphase value. This is most simply explained by assuming that recycling of receptors back to the cell surface is inhibited as cells enter mitosis but that internalisation continues for a short while, causing surface receptor depletion. In telophase recycling would resume before internalisation giving a temporary excess of surface transferrin receptors.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Scand J Immunol. 1973;2(3):273-90 - PubMed
    1. J Clin Pathol. 1974 Mar;27(3):254-6 - PubMed
    1. Science. 1975 Aug 1;189(4200):347-58 - PubMed
    1. Methods Cell Biol. 1975;10:157-72 - PubMed
    1. Biophys J. 1976 Nov;16(11):1315-29 - PubMed