doi: 10.1093/nar/4.9.3199.
The structure of the chromatin core particle in solution
- PMID: 561952
- PMCID: PMC342644
- DOI: 10.1093/nar/4.9.3199
Item in Clipboard
The structure of the chromatin core particle in solution
Nucleic Acids Res.
1977 Sep.
Free PMC article
Abstract
The shape and size of the nucleosomal core particle from chromatin has been examined by analysis of neutron and X-ray scattering data from dilute solutions. Calculations of scattering for many different models have been made and only one model was able to account for both the X-ray and neutron profiles. This model is an oblate structure with height about 50A and diameter 110A. The DNA is mainly confined to two annuli located at the top and bottom respectively of the core particle positioned on the outside of a compact protein core which has a height of about 40A and diameter about 73A.
Similar articles
-
Structure of nucleosomes, chromatin, and RNA polymerase-promoter complex as revealed by DNA-protein cross-linking.Cold Spring Harb Symp Quant Biol. 1983;47 Pt 1:503-10. doi: 10.1101/sqb.1983.047.01.060. Cold Spring Harb Symp Quant Biol. 1983. PMID: 6574856 No abstract available.
-
Neutron scatter and diffraction techniques applied to nucleosome and chromatin structure.Cell Biophys. 1986 Dec;9(1-2):35-66. doi: 10.1007/BF02797374. Cell Biophys. 1986. PMID: 2436800
-
Nuclease cleavage of chromatin at 100-nucleotide pair intervals.Nature. 1976 Dec 9;264(5586):517-22. doi: 10.1038/264517a0. Nature. 1976. PMID: 1004586
-
[Current insights into chromatin structure organization].Tsitologiia. 2012;54(4):298-306. Tsitologiia. 2012. PMID: 22724366 Review. Russian.
-
Structure of chromatin.Annu Rev Biochem. 1977;46:931-54. doi: 10.1146/annurev.bi.46.070177.004435. Annu Rev Biochem. 1977. PMID: 332067 Review. No abstract available.
Cited by
-
Spatial organization of histones and DNA in the nucleosome core particle: a model.Mol Biol Rep. 1980 Dec 31;6(4):219-23. doi: 10.1007/BF00777528. Mol Biol Rep. 1980. PMID: 7207471
-
Light scattering measurements supporting helical structures for chromatin in solution.Nucleic Acids Res. 1978 May;5(5):1571-80. doi: 10.1093/nar/5.5.1571. Nucleic Acids Res. 1978. PMID: 662693 Free PMC article.
-
DNA wrapping in nucleosomes. The linking number problem re-examined.Nucleic Acids Res. 1980 Oct 24;8(20):4803-20. doi: 10.1093/nar/8.20.4803. Nucleic Acids Res. 1980. PMID: 6255433 Free PMC article.
-
Experimental evidence for asymmetrical shielding of nucleosomal DNA by histones.Nucleic Acids Res. 1979 Dec 20;7(8):2419-29. doi: 10.1093/nar/7.8.2419. Nucleic Acids Res. 1979. PMID: 230466 Free PMC article.
-
Nucleosome core histone complex isolated gently and rapidly in 2 M NaCl is octameric.Proc Natl Acad Sci U S A. 1979 Oct;76(10):5178-82. doi: 10.1073/pnas.76.10.5178. Proc Natl Acad Sci U S A. 1979. PMID: 291932 Free PMC article.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
