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. 1970 Sep;119(3):489-92.
doi: 10.1042/bj1190489.

Phospholipid synthesis and degradation during the life-cycle of P815Y mast cells synchronized with excess of thymidine

J J Bergeron, A M Warmsley, C A Pasternak

Phospholipid synthesis and degradation during the life-cycle of P815Y mast cells synchronized with excess of thymidine

J J Bergeron et al. Biochem J. 1970 Sep.

Abstract

1. P815Y cells synchronized with excess of thymidine incorporate choline, proline and uridine throughout the cell cycle; the rate increases two- to four-fold during the S phase, when thymidine incorporation increases more than 15-fold. 2. Choline incorporated at any stage of the cell cycle turns over in a biphasic manner; stable and unstable components are each labelled maximally during the S phase. Total phospholipid also doubles predominantly during the S phase. 3. It is concluded that, despite turnover, choline incorporation is a useful measure of net phospholipid formation during the cell cycle.

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References

    1. Biochim Biophys Acta. 1968 Sep 17;163(2):218-25 - PubMed
    1. Fed Proc. 1969 Nov-Dec;28(6):1771-9 - PubMed
    1. J Biol Chem. 1959 Mar;234(3):466-8 - PubMed
    1. Biochem J. 1970 Sep;119(3):473-80 - PubMed
    1. FEBS Lett. 1969 Aug;4(3):161-163 - PubMed