Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1966 Mar 12;94(11):528-31.

The use of corticosteroid (dexamethasone) in the treatment of acute laryngotracheitis

P N Skowron, J A Turner, G A McNaughton
Clinical Trial

The use of corticosteroid (dexamethasone) in the treatment of acute laryngotracheitis

P N Skowron et al. Can Med Assoc J. .

Abstract

Many practitioners have considered that steroids, with their anti-inflammatory properties, should be efficacious in the treatment of acute laryngotracheitis. To examine this theory, 200 consecutive cases of acute laryngotracheitis admitted to The Hospital for Sick Children, Toronto, were included in a double-blind study using dexamethasone-21-phosphate and placebo according to a random selection code. All other therapy was kept constant. Each patient was assessed by one observer according to seven clinical parameters.The results of this study were subjected to statistical analysis and significantly favoured the steroid-treated group in four parameters only. In view of the risks inherent in steroid therapy, this degree of difference is not sufficient to warrant routine use of this drug for patients with acute laryngotracheitis.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. AMA Am J Dis Child. 1952 Apr;83(4):440-5 - PubMed
    1. Can Med Assoc J. 1954 Apr;70(4):401-4 - PubMed
    1. Can Med Assoc J. 1954 Nov;71(5):482-4 - PubMed

Publication types

LinkOut - more resources