Auto-antibodies of the IgD class
Clin Exp Immunol.
1970 Jun.
Abstract
Utilizing immunofluorescent techniques, antinuclear and antithyroid antibodies were demonstrated within the IgD class of immunoglobulins. Glomerular deposits of IgD were detected in three kidneys with glomerulonephritis and one renal allograft. Similar deposits were not present in four kidneys with respective diagnosis of interstitial nephritis, lupus nephritis, chronic glomerulonephritis, and focal glomerulonephritis.
IgD antibodies may be formed in response to a variety of antigenic stimuli and are present in some autoimmune disorders. The detection of glomerular deposits of IgD suggests that immunoglobulins of this class may be present in association with some immunologically induced lesions.
Similar articles
-
[Lupus nephritis: elution studies and the role of circulating antinuclear factors].Medicina (B Aires). 1970 Jul-Aug;30(4):372-9. Medicina (B Aires). 1970. PMID: 4098883 Spanish. No abstract available.
-
The immunopathogenesis of lupus nephritis.Adv Nephrol Necker Hosp. 1976;6:119-36. Adv Nephrol Necker Hosp. 1976. PMID: 65907 No abstract available.
-
Characterization of immunoglobulin G anti-glomerular basement membrane antibodies eluted from kidneys of patients with glomerulonephritis. II. IgG subtypes and in vitro complement fixation.J Immunol. 1971 Sep;107(3):678-84. J Immunol. 1971. PMID: 4999091 No abstract available.
-
[What is the role of autoimmune processes in nephropathies?].Monatsschr Kinderheilkd. 1990 Nov;138(11):724-9. Monatsschr Kinderheilkd. 1990. PMID: 2290431 Review. German.
-
Auto-immunity and systemic lupus erythematosus.Med Lab Technol. 1972 Apr;29(2):133-42. Med Lab Technol. 1972. PMID: 4116076 Review. No abstract available.
Cited by
-
Serum IgD concentrations in sarcoidosis and tuberculosis.Clin Exp Immunol. 1972 Feb;10(2):257-65. Clin Exp Immunol. 1972. PMID: 4625797 Free PMC article.
-
IgM and IgD concentrations in the serum and secretions of children with selective IgA deficiency.Clin Exp Immunol. 1983 Sep;53(3):689-96. Clin Exp Immunol. 1983. PMID: 6616961 Free PMC article.
-
Immunofluorescent investigations in cutaneous vasculitis. II. Histotopical demonstration of IgD and fibrin.Arch Dermatol Res (1975). 1975 Dec 10;254(2):215-24. doi: 10.1007/BF00586895. Arch Dermatol Res (1975). 1975. PMID: 766711
-
Immunoglobulin D: properties, measurement, and clinical relevance.Clin Diagn Lab Immunol. 2000 Mar;7(2):131-40. doi: 10.1128/CDLI.7.2.131-140.2000. Clin Diagn Lab Immunol. 2000. PMID: 10702483 Free PMC article. Review. No abstract available.
-
Rad52 mediates class-switch DNA recombination to IgD.Nat Commun. 2022 Feb 21;13(1):980. doi: 10.1038/s41467-022-28576-2. Nat Commun. 2022. PMID: 35190531 Free PMC article.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources