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. 1972 Jun;5(6):883-9.
doi: 10.1128/iai.5.6.883-889.1972.

Immunogenicity of egg-grown influenza vaccine: inhibition by immunization of recipients with host antigen

J Lindenmann

Immunogenicity of egg-grown influenza vaccine: inhibition by immunization of recipients with host antigen

J Lindenmann. Infect Immun. 1972 Jun.

Abstract

Rabbit antibody directed against normal allantoic fluid reduced the protective power of influenza vaccine prepared from egg-grown PR8 virus. A similar vaccine prepared from mouse lung virus was not inhibited. Preimmunization of mice with normal allantoic fluid or with egg-grown influenza B/Lee vaccine (crude or purified) inhibited the protective power of PR8 egg vaccine but did not affect a similar lung vaccine.

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