Potentiation of rifampicin and 5-fluorocytosine as antifungal antibiotics by amphotericin B (yeast-membrane permeability-ribosomal RNA-eukaryotic cell-synergism)
- PMID: 4550505
- PMCID: PMC427574
- DOI: 10.1073/pnas.69.1.196
Potentiation of rifampicin and 5-fluorocytosine as antifungal antibiotics by amphotericin B (yeast-membrane permeability-ribosomal RNA-eukaryotic cell-synergism)
Abstract
Amphotericin B potentiates the antifungal effects of 5-fluorocytosine and rifampicin, probably by increasing the penetration of these agents through the fungal cytoplasmic membrane.
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