doi: 10.1128/jb.108.1.410-414.1971.
Histidine regulation in Salmonella typhimurium. 8. Mutations of the hisT gene
- PMID: 4330739
- PMCID: PMC247079
- DOI: 10.1128/jb.108.1.410-414.1971
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Histidine regulation in Salmonella typhimurium. 8. Mutations of the hisT gene
J Bacteriol.
1971 Oct.
Abstract
The hisT gene, one of six genes in which mutation causes derepression of the histidine operon in Salmonella typhimurium, is shown to code for a protein that is not essential for the growth of the bacteria. This is indicated by the characterization of particular classes of mutations in the hisT gene: amber mutations, frame-shift mutations, and temperature-sensitive mutations that affect repression but not growth. In addition, the class of semilethal mutations was selected for but not found.
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