Hypokalemic paralysis in Sjögren's syndrome secondary to renal tubular acidosis
- PMID: 4001878
- DOI: 10.3109/03009748509102018
Hypokalemic paralysis in Sjögren's syndrome secondary to renal tubular acidosis
Abstract
A 62-year-old woman with Sjögren's syndrome, distal renal tubular acidosis and hypokalemic muscle paralysis is described. The sicca syndrome was nearly subclinical and went unrecognized for several years. The main and first manifestation to be expressed was that of hypokalemic muscle paralysis secondary to renal tubular acidosis. In the last decade several reports have appeared indicating that renal tubular acidosis is associated with Sjögren's syndrome. The data in this report support the view that adult onset distal renal tubular acidosis is often a disorder of an autoimmune disease, frequently that of Sjögren's syndrome. The complications to renal tubular acidosis such as hypokalemic muscle paralysis or chronic muscle weakness, nephrolithiasis, and osteomalacia can be avoided if the diagnosis of renal tubular acidosis is made and corrective alkali therapy is maintained.
Similar articles
-
Hypokalemic periodic paralysis in Sjögren's syndrome.Arch Intern Med. 1981 Nov;141(12):1671-3. Arch Intern Med. 1981. PMID: 7305577
-
Hypokalemic paralysis and osteomalacia secondary to renal tubular acidosis in a case with primary Sjögren's syndrome.Mod Rheumatol. 2006;16(1):48-51. doi: 10.1007/s10165-005-0446-2. Mod Rheumatol. 2006. PMID: 16622725
-
An unusual case of hypokalemic paralysis associated with primary Sjogren's syndrome.J Ark Med Soc. 2008 Jun;104(12):286-7. J Ark Med Soc. 2008. PMID: 18564466
-
Renal tubular acidosis without interstitial nephritis in Sjögren's syndrome: a case report and review of the literature.BMC Nephrol. 2023 Aug 15;24(1):237. doi: 10.1186/s12882-023-03290-3. BMC Nephrol. 2023. PMID: 37582721 Free PMC article. Review.
-
Hypokalemic rhabdomyolysis: an unusual presentation of Sjogren's syndrome.BMJ Case Rep. 2013 Oct 28;2013:bcr2013201345. doi: 10.1136/bcr-2013-201345. BMJ Case Rep. 2013. PMID: 24165505 Free PMC article. Review.
Cited by
-
Hypokalaemic paralysis revealing Sjögren syndrome in an elderly man.J Clin Pathol. 1999 Feb;52(2):157-8. doi: 10.1136/jcp.52.2.157. J Clin Pathol. 1999. PMID: 10396249 Free PMC article.
-
A primary Sjögren's syndrome patient with distal renal tubular acidosis, who presented with symptoms of hypokalemic periodic paralysis: Report of a case study and review of the literature.Rheumatol Int. 2005 Nov;26(1):86-9. doi: 10.1007/s00296-005-0587-9. Epub 2005 Feb 3. Rheumatol Int. 2005. PMID: 15690142
-
Pathophysiology and management of hypokalemia: a clinical perspective.Nat Rev Nephrol. 2011 Feb;7(2):75-84. doi: 10.1038/nrneph.2010.175. Nat Rev Nephrol. 2011. PMID: 21278718 Review.
-
Renal tubular dysfunction in primary Sjögren's syndrome: clinical studies in 27 patients.Clin Rheumatol. 1991 Mar;10(1):23-7. doi: 10.1007/BF02208028. Clin Rheumatol. 1991. PMID: 2065503
-
Hypokalemic periodic paralysis in Sjogren's syndrome secondary to distal renal tubular acidosis.Rheumatol Int. 2013 Jul;33(7):1879-82. doi: 10.1007/s00296-011-2322-z. Epub 2012 Jan 3. Rheumatol Int. 2013. PMID: 22212410
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
