Adjuvant CDK4/6 inhibitors in hormone receptor-positive early breast cancer: one fits all?
- PMID: 39534583
- PMCID: PMC11557154
- DOI: 10.21037/tbcr-24-41
Adjuvant CDK4/6 inhibitors in hormone receptor-positive early breast cancer: one fits all?
Keywords: CDK4/6 inhibitors; early breast cancer (EBC); hormone receptor positive (HR+); ribociclib.
Conflict of interest statement
Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://tbcr.amegroups.org/article/view/10.21037/tbcr-24-41/coif). M.C. serves as an unpaid editorial board member of Translational Breast Cancer Research from April 2023 to March 2025. M.C. reports personal fees from Lilly, Sermonix, Data Genomics, Foundation Medicine, Guardant Health, Celcuity, Iylon, and Ellipses and grants and personal fees from Pfizer, AZ and Menarini, all outside the submitted work. E.N. is supported by an American-Italian Cancer Foundation Post-Doctoral Research Fellowship. The other author has no conflicts of interest to declare.
Comment on
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Ribociclib plus Endocrine Therapy in Early Breast Cancer.N Engl J Med. 2024 Mar 21;390(12):1080-1091. doi: 10.1056/NEJMoa2305488. N Engl J Med. 2024. PMID: 38507751 Clinical Trial.
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References
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- Johnston SRD, Toi M, O'Shaughnessy J, et al. Abemaciclib plus endocrine therapy for hormone receptor-positive, HER2-negative, node-positive, high-risk early breast cancer (monarchE): results from a preplanned interim analysis of a randomised, open-label, phase 3 trial. Lancet Oncol 2023;24:77-90. 10.1016/S1470-2045(22)00694-5 - DOI - PMC - PubMed
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