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. 2024 Nov 12;20(3):240105.
doi: 10.1183/20734735.0105-2024. eCollection 2024 Oct.

Highlights from the Respiratory Failure and Mechanical Ventilation Conference 2024

Clara Bianquis  1 , Giancarlo De Leo  2 , Giorgio Morana  3 , Marta Duarte-Silva  4 , Santi Nolasco  3   5 , Rūdolfs Vilde  6   7 , Athiwat Tripipitsiriwat  8 , Pedro Viegas  9 , Martins Purenkovs  10   11 , Marieke Duiverman  12   13 , Christian Karagiannids  14 , Christoph Fisser  15
Affiliations

Highlights from the Respiratory Failure and Mechanical Ventilation Conference 2024

Clara Bianquis et al. Breathe (Sheff). .

Abstract

The Respiratory Intensive Care Assembly of the European Respiratory Society gathered in Berlin to organise the third Respiratory Failure and Mechanical Ventilation Conference in February 2024. The conference covered key points of acute and chronic respiratory failure in adults. During the 3-day conference ventilatory strategies, patient selection, diagnostic approaches, treatment and health-related quality of life topics were addressed by a panel of international experts. In this article, lectures delivered during the event have been summarised by early career members of the Assembly and take-home messages highlighted.

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Conflict of interest statement

Conflict of interest: C. Bianquis reports grants from ASTEN santé and support for attending meetings from Vitalaire. G. De Leo, G. Morana, M. Duarte-Silva and S. Nolasco have nothing to disclose. R. Vilde reports support for attending meetings from Chiesi and has a leadership role with Latvian Junior doctors’ association as a Board member. A. Tripipitsiriwat and P. Viegas have nothing to disclose. M. Purenkovs reports leadership roles with the Latvian Society of Sleep Medicine (Board member), Latvian Society of Innovative Pneumonology and Respiratory Medicine (board member), and Latvian Society of Tuberculosis and Lung Diseases doctors (board member). M. Duiverman reports grants from Fisher & Paykel (High-TeC trial), Vivisol BV (High-TeC trial and Noctivent trial), RESMED Ltd (RECAPTURE trial), Löwenstein BV (Noctivent trial), and Secure BV (Noctivent trial), payment or honoraria for lectures from Vivisol BV, Chiesi, Breas, and AstraZeneca, and a leadership role with ERS as the chair of the NIV group of Assembly 2. C. Karagiannidis and C. Fisser have nothing to disclose.

Figures

FIGURE 1
FIGURE 1
Figure illustrating the pathophysiological effects resulting from over-recruitment and conversely caused by weakness of the expiratory muscles. Over-recruitment leads to an increase in carbon dioxide production and pleural pressure, with the overall consequences of dynamic airway collapse, a rise in end-expiratory lung volume, small airway and alveolar injury, and finally, atelectasis and tidal recruitment leading to acute respiratory distress syndrome (ARDS). Weakness of the expiratory muscles leads to a reduction in ventilation and coughing capacity, and a drop in the clearance of secretions.
FIGURE 2
FIGURE 2
Respiratory mechanical parameters during spontaneous breathing (SB), low-intensity (Li-) noninvasive positive pressure ventilation (NPPV) and high-intensity (Hi-) NPPV. Transdiaphragmatic pressure (Pdi) was lowest during Hi-NPPV. Paw: airway pressure; Ppl: pleural pressure. Reproduced from [74] with permission.
See this image and copyright information in PMC

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