Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2024;49(1):884-897.
doi: 10.1159/000541848. Epub 2024 Oct 15.

Nanocarrier-Based Drug Delivery Systems Targeting Kidney Diseases

Laura Zucaro  1   2 , Consiglia Longobardi  1   2 , Antonio Miele  1   2 , Antonio Villanova  1   2 , Yoko Suzumoto  1   3
Affiliations
Free article
Review

Nanocarrier-Based Drug Delivery Systems Targeting Kidney Diseases

Laura Zucaro et al. Kidney Blood Press Res. 2024.
Free article

Abstract

Background: The potential applications of nanotechnology in the medical field have become increasingly recognized in recent years. Nanocarriers have emerged as a versatile tool, offering a wide range of applications due to their unique properties. In addition to the targeted drugs delivery, nanocarriers have also proven to be extremely effective in imaging and diagnostics. Continuous advances in nanotechnology have paved the way for innovative solutions to complex challenges in human health, shaping the future of nanotechnology and its applications.

Summary: By exploring different types of nanoparticles, this review delves into the different characteristics that can be tailored to enhance their kidney access. Although the structural complexity of the kidney may prevent nanocarriers passage, optimization of nanocarrier characteristics such as shape, size, charge, and surface modifications may overcome these barriers, allowing for targeted delivery. By harnessing the potential of nanoparticles, researchers aim to develop targeted and efficient therapies that can address various kidney-related disorders.

Key messages: This review highlights the promising advancements in nanotechnology and their potential impact on improving the therapeutic outcomes for several kidney diseases.

Keywords: Glomeruli; Kidney diseases; Nanomedicine; Renal tubules; Targeted drug delivery.

PubMed Disclaimer

Similar articles

See all similar articles

LinkOut - more resources