Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2024 Aug 27:19:8831-8846.
doi: 10.2147/IJN.S474888. eCollection 2024.

Nanoparticles as a Novel Platform for Cardiovascular Disease Diagnosis and Therapy

Chuanyun Tang #  1 , Kexun Zhou #  2 , Di Wu #  1 , Hong Zhu  2
Affiliations
Review

Nanoparticles as a Novel Platform for Cardiovascular Disease Diagnosis and Therapy

Chuanyun Tang et al. Int J Nanomedicine. .

Abstract

Cardiovascular disease (CVD) is a major global health issue with high mortality and morbidity rates. With the advances in nanotechnology, nanoparticles are receiving increasing attention in diagnosing and treating CVD. Previous studies have explored the use of nanoparticles in noninvasive diagnostic technologies, such as magnetic resonance imaging and computed tomography. Nanoparticles have been extensively studied as drug carriers and prognostic factors, demonstrating synergistic efficacy. This review summarized the current applications of nanoparticles in CVD and discussed their opportunities and challenges for further exploration.

Keywords: cardiovascular disease; diagnosis; nanoparticle functionalization; nanoparticles; therapy.

PubMed Disclaimer

Conflict of interest statement

The authors report no conflicts of interest in this work.

Figures

Figure 1
Figure 1
Schematic about different nanomaterials and their characteristic features. Advancements in three primary classifications of nanoparticles and their characteristic features. (Created by Figdraw).
Figure 2
Figure 2
Overview of nanotechnology in CVD. Nanotheranostics combine the functions of diagnosis and treatment and are used in CVD. (A) commonly used nanocarriers (liposomes, organic polymers, biomimetic particles, and inorganic materials) combine traditional diagnostic and treatment methods. (B) nanoparticles can be injected directly to prevent or alleviate the onset of atherosclerosis, which is the most common fatal cardiovascular disease. (C) nanoparticles can be used to improve the function of heart valves, myocardial patches, and vascular stents or directly for in vivo injection. (Created by Figdraw).
See this image and copyright information in PMC

Cited by

References

    1. Gupta AS. Nanomedicine approaches in vascular disease: a review. Nanomedicine. 2011;7(6):763–779. doi:10.1016/j.nano.2011.04.001 - DOI - PubMed
    1. Diez-Pascual AM, Rahdar A. Functional nanomaterials in biomedicine: current uses and potential applications. ChemMedChem. 2022;17(16):e202200142. doi:10.1002/cmdc.202200142 - DOI - PMC - PubMed
    1. Patra JK, Das G, Fraceto LF, et al. Nano-based drug delivery systems: recent developments and future prospects. J Nanobiotechnology. 2018;16(1):71. doi:10.1186/s12951-018-0392-8 - DOI - PMC - PubMed
    1. Heshmati Aghda N, Dabbaghianamiri M, Tunnell JW, Betancourt T. Design of smart nanomedicines for effective cancer treatment. Int J Pharm. 2022;621:121791. doi:10.1016/j.ijpharm.2022.121791 - DOI - PubMed
    1. Corma A, Botella P, Rivero-Buceta E. Silica-based stimuli-responsive systems for antitumor drug delivery and controlled release. Pharmaceutics. 2022;14(1):110. doi:10.3390/pharmaceutics14010110 - DOI - PMC - PubMed

MeSH terms

LinkOut - more resources