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Review
. 2024 Oct;122(4):447-454.
doi: 10.1111/mmi.15301. Epub 2024 Aug 3.

Flagellar protein FliL: A many-splendored thing

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Review

Flagellar protein FliL: A many-splendored thing

Jonathan D Partridge et al. Mol Microbiol. 2024 Oct.

Abstract

FliL is a bacterial flagellar protein demonstrated to associate with, and regulate ion flow through, the stator complex in a diverse array of bacterial species. FliL is also implicated in additional functions such as stabilizing the flagellar rod, modulating rotor bias, sensing the surface, and regulating gene expression. How can one protein do so many things? Its location is paramount to understanding its numerous functions. This review will look at the evidence, attempt to resolve some conflicting findings, and offer new thoughts on FliL.

Keywords: FliL; flagella; motor torque; rotor bias; stators; surface sensing; swarming; swimming.

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References

REFERENCES

    1. Aldridge, P. & Jenal, U. (1999) Cell cycle‐dependent degradation of a flagellar motor component requires a novel‐type response regulator. Molecular Microbiology, 32, 379–391.
    1. Attmannspacher, U., Scharf, B.E. & Harshey, R.M. (2008) FliL is essential for swarming: motor rotation in absence of FliL fractures the flagellar rod in swarmer cells of Salmonella enterica. Molecular Microbiology, 68, 328–341.
    1. Baker, A.E. & O'Toole, G.A. (2017) Bacteria, rev your engines: stator dynamics regulate Flagellar motility. Journal of Bacteriology, 199, 1–8.
    1. Belas, R., Horikawa, E., Aizawa, S. & Suvanasuthi, R. (2009) Genetic determinants of Silicibacter sp. TM1040 motility. Journal of Bacteriology, 191, 4502–4512.
    1. Belas, R., Simon, M. & Silverman, M. (1986) Regulation of lateral flagella gene transcription in Vibrio parahaemolyticus. Journal of Bacteriology, 167, 210–218.

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