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Review
. 2024 Oct;48(5):3381-3385.
doi: 10.1007/s11259-024-10464-3. Epub 2024 Jul 23.

Ulcerative and pyogranulomatous pododermatitis due to Pseudomonas luteola infection in a domestic ferret (Mustela putorius furo): a case report with literature review of this emerging zoonotic disease in ferrets

Jacobo Giner  1   2 , María Eugenia Lebrero  2   3 , Diego López-Sahuquillo  1 , Sergio Villanueva-Saz  4   5   6 , Carles Juan-Sallés  7 , Teresa Navarro  3 , Antonio Fernández  2   3   8 , Diana Marteles  9   10 , Álex Gómez  3   8
Affiliations
Review

Ulcerative and pyogranulomatous pododermatitis due to Pseudomonas luteola infection in a domestic ferret (Mustela putorius furo): a case report with literature review of this emerging zoonotic disease in ferrets

Jacobo Giner et al. Vet Res Commun. 2024 Oct.

Abstract

Pseudomonas luteola (P.luteola), formerly called Chryseomonas luteola, is a strict aerobic gram-negative bacillus, 0.8 to 1.0 µm wide and 1.5 to 2.5 µm long, considered an opportunistic pathogen found ubiquitously in humid environments, both in soil and water. It sporadically causes disease in animals and immunosuppressed humans or those subjected to invasive procedures such us peritoneal dialysis or catheterization. In ferrets, this infection was first described in Spain in 2012 and since then, cases have appeared occasionally in Finland, Austria, Australia, France, the United States and also in Spain. This pathogen is considered an emerging zoonotic disease in ferrets, causing respiratory disease, panniculitis, and abscesses due to pyogranulomatous or suppurative inflammation predominantly of the pleura, lung, mediastinum, panniculus or salivary glands, frequently with lethal consequences. The clinical case of a ferret, infected by Pseudomona luteola, presenting with ulcerative suppurative pododermatitis and ipsilateral popliteal purulent lymphadenitis, is described. Together with a complete resolution of the clinical case by means of a non-invasive medical management likely due to the rapid detection, identification, and treatment of the infection.

Keywords: Pseudomonas luteola; Ferret; Pododermatitis; Spain.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Clinical progression of the P. luteola associated pododermatitis. a). Severe, ulcerative and edematous pododermatitis previous to treatment; b). Improvement of pododermatitis after treatment; c). Complete resolution 1 month after completion of treatment
Fig. 2
Fig. 2
Fine needle aspiration (FNA) from the affected right popliteal lymph node. a). Popliteal lymph node enlargement; b). The sample was ejected on the slide for Diff-Quick staining and cytological examination
Fig. 3
Fig. 3
Histopathological analysis from sampled pododermatitis. a). Complete ulceration and colonies of cocobacilli and serpentine bacilli with a clear halo infiltrating the superficial and deep dermis (arrows). HE, Bar: 1000 μm.; b). Colonies (arrows) surrounded by neutrophils and macrophages (arrowhead). HE, Bar: 100 μm
See this image and copyright information in PMC

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