Nanomaterials in the treatment and diagnosis of rheumatoid arthritis: Advanced approaches

doi:10.1016/j.slast.2024.100146

Review

. 2024 Aug;29(4):100146.

doi: 10.1016/j.slast.2024.100146. Epub 2024 Jun 4.

Nanomaterials in the treatment and diagnosis of rheumatoid arthritis: Advanced approaches

Affiliations

¹ Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan.
² Department of Power Mechanical Engineering, National Tsing Hua University, Hsinchu, Taiwan.
³ The Ph.D. Program for Translational Medicine, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.
⁴ Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Shuang Ho Hospital, New Taipei City, Taiwan; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
⁵ The Ph.D. Program in Medical Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan; School of Medical Laboratory Science and Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.
⁶ Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan; Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei, Taiwan; Department of Chemistry, National Taiwan Normal University, Taipei, Taiwan.
⁷ Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan; Sustainable Electrochemical Energy Development (SEED) Center, National Taiwan University of Science and Technology, Taipei, Taiwan; Advanced Manufacturing Research Center, National Taiwan University of Science and Technology, Taipei, Taiwan. Electronic address: weshsiao@mail.ntust.edu.tw.

PMID: 38844139
DOI: 10.1016/j.slast.2024.100146

Free article

Review

Nanomaterials in the treatment and diagnosis of rheumatoid arthritis: Advanced approaches

Stefanny Angela et al. SLAS Technol. 2024 Aug.

Free article

. 2024 Aug;29(4):100146.

doi: 10.1016/j.slast.2024.100146. Epub 2024 Jun 4.

Authors

Affiliations

¹ Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan.
² Department of Power Mechanical Engineering, National Tsing Hua University, Hsinchu, Taiwan.
³ The Ph.D. Program for Translational Medicine, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.
⁴ Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Shuang Ho Hospital, New Taipei City, Taiwan; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
⁵ The Ph.D. Program in Medical Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan; School of Medical Laboratory Science and Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.
⁶ Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan; Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei, Taiwan; Department of Chemistry, National Taiwan Normal University, Taipei, Taiwan.
⁷ Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan; Sustainable Electrochemical Energy Development (SEED) Center, National Taiwan University of Science and Technology, Taipei, Taiwan; Advanced Manufacturing Research Center, National Taiwan University of Science and Technology, Taipei, Taiwan. Electronic address: weshsiao@mail.ntust.edu.tw.

PMID: 38844139
DOI: 10.1016/j.slast.2024.100146

Abstract

Rheumatoid arthritis (RA), a chronic inflammatory condition that affects persons between the ages of 20 and 40, causes synovium inflammation, cartilage loss, and joint discomfort as some of its symptoms. Diagnostic techniques for RA have traditionally been split into two main categories: imaging and serological tests. However, significant issues are associated with both of these methods. Imaging methods are costly and only helpful in people with obvious symptoms, while serological assays are time-consuming and require specialist knowledge. The drawbacks of these traditional techniques have led to the development of novel diagnostic approaches. The unique properties of nanomaterials make them well-suited as biosensors. Their compact dimensions are frequently cited for their outstanding performance, and their positive impact on the signal-to-noise ratio accounts for their capacity to detect biomarkers at low detection limits, with excellent repeatability and a robust dynamic range. In this review, we discuss the use of nanomaterials in RA theranostics. Scientists have recently synthesized, characterized, and modified nanomaterials and biomarkers commonly used to enhance RA diagnosis and therapy capabilities. We hope to provide scientists with the promising potential that nanomaterials hold for future theranostics and offer suggestions on further improving nanomaterials as biosensors, particularly for detecting autoimmune disorders.

Keywords: Biomarker; Biosensor; Diagnosis; Nanomaterials; Rheumatoid arthritis; Therapy.

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Conflict of interest statement

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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Nanomaterials in the treatment and diagnosis of rheumatoid arthritis: Advanced approaches

Affiliations

Nanomaterials in the treatment and diagnosis of rheumatoid arthritis: Advanced approaches

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Abstract

Conflict of interest statement

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Conflict of interest statement

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