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Case Reports
. 2024 May 29:12:2050313X241256825.
doi: 10.1177/2050313X241256825. eCollection 2024.

Neurosyphilis with sequential respiratory complications: A case report highlighting diagnostic and treatment challenges

Affiliations
Case Reports

Neurosyphilis with sequential respiratory complications: A case report highlighting diagnostic and treatment challenges

Hanifa Majid et al. SAGE Open Med Case Rep. .

Abstract

In this case report, we describe the presentation and clinical course of a 25-year-old male with a complex medical history and a fatal outcome due to neurosyphilis. The diagnosis of neurosyphilis-related complications. Neurosyphilis, a variant of tertiary syphilis, is a rare condition but can present with a wide range of neurological symptoms. This makes its diagnosis challenging. The study aims to report and discuss neurosyphilis in a young male, resulting in respiratory complications, and explore the clinical presentation, diagnostic and process, treatment challenges it poses to a tertiary care setup of a third-world country regimen, and the profound significance of this particular case.

Keywords: Neurosyphilis; Treponema pallidum; complications; respiratory.

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Conflict of interest statement

The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Post-contrast magnetic resonance imaging showing abnormal signal intensity areas involving bilateral basal ganglia, thalami, and periventricular deep white matter (red arrow).
Figure 2.
Figure 2.
An MRI of the brain; (A) without contrast and (B) with contrast. A non-enhancing, fluid signal intensity area in the white matter of the Right Parietal lobe shows peripheral high signal and restriction (yellow arrow).
Figure 3.
Figure 3.
An anterior/posterior view of the chest X-ray showing right-sided consolidation (red arrow) and left-sided pneumothorax (purple arrows).

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References

    1. Golden MR, Marra CM, Holmes KK. Update on syphilis: resurgence of an old problem. JAMA 2003; 290(11): 1510–1514. - PubMed
    1. Gjestland T. The Oslo study of untreated syphilis, an epidemiologic investigation of the natural course of syphilitic infection based upon a restudy of the Boeck-Bruusgaard material. Acta Derm Venereol 1955; 35: S-34. - PubMed
    1. Tuddenham S, Ghanem KG. Neurosyphilis: knowledge gaps and controversies. Sex Transm Dis 2018; 45(3): 147–151. - PMC - PubMed
    1. Landry T, Smyczek P, Cooper R, et al.. Retrospective review of tertiary and neurosyphilis cases in Alberta, 1973–2017. BMJ Open 2019; 9(6): e025995. - PMC - PubMed
    1. Tong ML, Liu LL, Zeng YL, et al.. Laboratory findings in neurosyphilis patients with epileptic seizures alone as the initial presenting symptom. Diagn Microbiol Infect Dis 2013; 75(4): 377–380. - PubMed

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