Comparative Study
doi: 10.1016/0014-5793(85)80989-3.
Sequence of the OXA2 beta-lactamase: comparison with other penicillin-reactive enzymes
- PMID: 3876949
- DOI: 10.1016/0014-5793(85)80989-3
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Comparative Study
Sequence of the OXA2 beta-lactamase: comparison with other penicillin-reactive enzymes
FEBS Lett.
.
Free article
Abstract
The nucleotide sequence of the unusual plasmid-mediated OXA2 beta-lactamase is presented, and compared with other beta-lactamases. The OXA2 enzyme has similar features at the presumed active site, but no other significant regions of homology with other penicillin-reactive enzymes. The active site homology may therefore represent convergent evolution of otherwise dissimilar genes.
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