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. 2024 May 6;32(spe1):e268544.
doi: 10.1590/1413-785220243201e268544. eCollection 2024.

HAS THE AGING OF BRAZILIANS IMPACTED THE OCCURRENCE OF OSTEO-CARTILAGINOUS NEOPLASMS?

Marcelo Tomio Kohara  1 , Gustavo Ferrareto Pires  1 , André Marson Sanches  1 , Rodrigo Pereira Amarante  1 , Gabriela Caponero de Brito  1 , Fernando Adami  2
Affiliations

HAS THE AGING OF BRAZILIANS IMPACTED THE OCCURRENCE OF OSTEO-CARTILAGINOUS NEOPLASMS?

Marcelo Tomio Kohara et al. Acta Ortop Bras. .

Abstract
in English, Portuguese

Cancer cases and survival have increased significantly in recent decades.

Objective: In this study, we sought to evidence whether bone, joint and cartilage neoplasms are increasing with the aging of the Brazilian population, using the analysis of the DATASUS and IBGE databases, between 1979 and 2020.

Methods: We compared the means and the proportion of death in Brazil, to observe the confidence interval overlaps, separated by region. Comparison between genders, age group, death and specific rate were compared via proportion tests and the trend was investigated via time series analysis.

Results: Through the analyses, we can see that there is an increasing trend of cases, about 2.5 times in the period. Separated by region, the Southeast stands out, with a number of deaths about 6 times higher than other regions.

Conclusion: Metastatic carcinoma is the most common neoplasm treated by orthopedic surgeons, and it is essential to adapt to this future projection, with cases of pathological bone involvement resulting from metastatic carcinomas, increasingly present in the routine of orthopedic surgeons. Level of Evidence IV, Cross-Sectional Observational Study.

Os casos oncológicos e a sobrevida aumentaram expressivamente nas últimas décadas. Objetivo: Investigar se as neoplasias de osso, articulação e cartilagem estão aumentando com o envelhecimento da população brasileira, por meio da análise das bases de dado do Sistema Único de Saúde (DATASUS) e do Instituto Brasileiro de Geografia e Estatística (IBGE), entre os anos de 1979 e 2020. Métodos: Realizamos a comparação de médias e de proporção de morte entre as regiões do Brasil para observar as sobreposições de intervalo de confiança em cada região. A comparação entre sexo, faixa etária, óbito e taxa específica foi feita via testes de proporção, e a tendência foi investigada via análise de séries temporais. Resultados: Foi evidenciada uma tendência crescente dos casos de neoplasia, com um aumento de cerca de 2,5 vezes no período analisado. Entre as regiões do Brasil, destacou-se o Sudeste, com número de mortes cerca de seis vezes maior que outras regiões. Conclusão: O carcinoma metastático é a neoplasia mais comum tratada pelos cirurgiões ortopédicos, e é fundamental nos adequarmos a essa projeção futura, com casos de comprometimento ósseo patológicos decorrentes de carcinomas metastáticos cada vez mais presentes na rotina do cirurgião ortopédico. Nível de Evidência IV, Estudo Observacional Transversal.

Keywords: Aging; Bone Neoplasms; Brazil; Cartilage; Epidemiology; Joint.

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Conflict of interest statement

All authors declare no potential conflict of interest related to this article.

Figures

Figure 1.
Figure 1.. Time trend analysis and projection of deaths over the years.
Figure 2.
Figure 2.. Time trend analysis and projection of the proportions of deaths due to cancer over the years.
Figure 3.
Figure 3.. Analysis of variance (ANOVA) comparing the means of death due to cancer between regions of Brazil.
Figure 4.
Figure 4.. Comparison according to primary location (C40-C41) between the periods 1979-1983 and 2016-2020.
See this image and copyright information in PMC

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