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Comparative Study
. 2024 Sep:51:26-31.
doi: 10.1016/j.prrv.2024.04.001. Epub 2024 Apr 4.

A comparison of peak cough flow and peak expiratory flow in children with neuromuscular disorders

H Fitzgerald  1 , B Kennedy  2 , D A Fitzgerald  3 , H Selvadurai  3
Affiliations
Comparative Study

A comparison of peak cough flow and peak expiratory flow in children with neuromuscular disorders

H Fitzgerald et al. Paediatr Respir Rev. 2024 Sep.

Abstract

Spirometry and peak cough flow testing (PCF) are commonly used in the respiratory assessment of children with a neuromuscular disorder (NMD). Testing uses two different machines, increases laboratory time, costs and resource utilisation. No studies have assessed the correlation between peak expiratory flow (PEF) obtained from spirometry and PCF in children with NMD using one device. An audit of children with a NMD managed at the Children's Hospital at Westmead in 2022-2024 aged < 20 years who performed spirometry and PCF testing on the same device (Vyaire Body BoxTM, Ultrasonic flow meter-based, or Vyaire PneumotachographTM, Pneumotach flow meter-based; Germany) was conducted to assess the correlation between PCF and PEF. Fifty-one sets of testing were identified, and 40 subjects (9F) had reproducible testing and were included. Median (range) age was 14.95 (7.20-19.00) years. Median PEF (L/min) was 4.05 (1.22-10.26) and median PCF (L/min) was 4.29 (1.69-10.82). PEF and PCF had a strong Pearson's correlation coefficient, (R = 0.97, p = 0.03). The coefficient of determination was 0.93. If laboratory resources permit, spirometry should be the test of choice for children with NMD. On average, spirometry required multiple practices to achieve reproducibility to meet ATS/ERS standards. PCF testing can be utilised for children where performing technically acceptable spirometry is not possible.

Keywords: Children; Neuromuscular Disorders; Peak Cough Flow; Peak Expiratory Flow; Spirometry.

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Conflict of interest statement

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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