Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2024 Feb 6;17(2):212.
doi: 10.3390/ph17020212.

Recent Advances in the Management of Rosacea through Natural Compounds

Iulia Semenescu  1   2 , Diana Similie  1   2 , Zorita Diaconeasa  3 , Corina Danciu  1   2
Affiliations
Review

Recent Advances in the Management of Rosacea through Natural Compounds

Iulia Semenescu et al. Pharmaceuticals (Basel). .

Abstract

Rosacea is a chronic skin disorder that affects more than 5% of the world's population, with the number increasing every year. Moreover, studies show that one-third of those suffering from rosacea report a degree of depression and are less compliant with treatment. Despite being the subject of prolonged studies, the pathogenesis of rosacea remains controversial and elusive. Since most medications used for the management of this pathology have side effects or simply do not yield the necessary results, many patients lose trust in the treatment and drop it altogether. Thus, dermato-cosmetic products with natural ingredients are gaining more and more notoriety in front of synthetic ones, due to the multiple benefits and the reduced number and intensity of side effects. This review is a comprehensive up-to-date report of studies that managed to prove the beneficial effects of different botanicals that may be useful in the short and long-term management of rosacea-affected skin. Based on recent preclinical and clinical studies, this review describes the mechanisms of action of a large array of phytochemicals responsible for alleviating the clinical symptomatology of the disease. This is useful in further aiding and better comprehending the way plant-based products may help in managing this complex condition, paving the way for research in this area of study.

Keywords: anti-inflammatory; antierythematous; antimicrobial; antioxidant; natural compounds; rosacea.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Main factors that contribute to the appearance of rosacea [20,21,22,23,24].
Figure 2
Figure 2
Main triggers of rosacea.
Figure 3
Figure 3
The main useful actions of plants in the management of rosacea.
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Korting H.C., Schöllmann C. Current Topical and Systemic Approaches to Treatment of Rosacea. J. Eur. Acad. Dermatol. Venereol. 2009;23:876–882. doi: 10.1111/j.1468-3083.2009.03167.x. - DOI - PubMed
    1. Gether L., Overgaard L.K., Egeberg A., Thyssen J.P. Incidence and Prevalence of Rosacea: A Systematic Review and Meta-Analysis. Br. J. Dermatol. 2018;179:282–289. doi: 10.1111/bjd.16481. - DOI - PubMed
    1. Scheinfeld N., Berk T. A Review of the Diagnosis and Treatment of Rosacea. Postgrad. Med. 2010;122:139–143. doi: 10.3810/pgm.2010.01.2107. - DOI - PubMed
    1. Wollina U., Verma S.B. Rosacea and Rhinophyma: Not Curse of the Celts but Indo Eurasians. J. Cosmet. Dermatol. 2009;8:234–235. doi: 10.1111/j.1473-2165.2009.00456.x. - DOI - PubMed
    1. Wilkin J., Dahl M., Detmar M., Drake L., Feinstein A., Odom R., Powell F. Standard Classification of Rosacea: Report of the National Rosacea Society Expert Committee on the Classification and Staging of Rosacea. J. Am. Acad. Dermatol. 2002;46:584–587. doi: 10.1067/mjd.2002.120625. - DOI - PubMed

Grants and funding

This research received no external funding.

LinkOut - more resources