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. 2024 Feb 15;13(4):1096.
doi: 10.3390/jcm13041096.

Predictors of Revascularization in Patients with Unstable Angina

Jan Budzianowski  1   2   3 , Wojciech Faron  3 , Janusz Rzeźniczak  4 , Marek Słomczyński  4 , Dariusz Hiczkiewicz  2   3 , Jacek Olejniczak  5 , Jarosław Hiczkiewicz  2   3 , Paweł Burchardt  1   4   6
Affiliations

Predictors of Revascularization in Patients with Unstable Angina

Jan Budzianowski et al. J Clin Med. .

Abstract

Background: The factors that determine the necessity of coronary artery revascularization in patients with unstable angina (UA) have been supported by limited data. Therefore, this study aimed to identify the predictors of revascularization in patients with UA.

Methods: The study included the recorded data of 3668 patients with UA who underwent cardiac catheterization (age 66 ± 9.2, men 70%); 2615 of them (71%) underwent revascularization (percutaneous transluminal coronary angioplasty (PTCA), coronary artery bypass graft (CABG), or hybrid revascularization. The remaining 1053 patients (29%) had no significant coronary stenosis and were regarded as controls. Multivariable logistic regression analysis was performed to separate the predictors of revascularization.

Results: It was found that severe angina (OR 2.7, 95%CI 1.9-3.7), male gender (OR 1.4, 95%CI 1.1-1.7), and hyperlipidemia were the predictors of revascularization. It was also noted that intraventricular conduction disorders including left and right bundle branch blocks and a history of previous revascularization and myocardial infarction were associated with lower odds of revascularization.

Conclusion: Overall, however, the predictive value of the studied factors proved to be poor and may still point to the multifactorial nature of significant coronary artery stenosis and the need for revascularization in patients with UA.

Keywords: acute coronary syndrome; coronary artery bypass graft; percutaneous coronary intervention; unstable angina.

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Conflict of interest statement

The authors have disclosed no conflicts of interest.

Figures

Figure 1
Figure 1
The percentage of UA individuals requiring and not requiring coronary revascularization.
Figure 2
Figure 2
ROC curves of total cholesterol levels for the diagnostic ability of revascularization in UA. AUC for total cholesterol (blue line), reference line (red line).
Figure 3
Figure 3
ROC curves of HDL and LDL-cholesterol levels for the diagnostic ability of revascularization in UA. AUC for HDL and LDL cholesterol (blue lines), reference lines (red lines).
Figure 4
Figure 4
ROC curves of MCV and MPV for the diagnostic abilities of revascularization in UA. AUC for MCV and MPV (blue lines), reference lines (red lines).
Figure 5
Figure 5
ROC curves of platelets and prothrombin time for the diagnostic abilities of revascularization in UA. AUC for PLT and PT (blue lines), reference lines (red lines).
Figure 6
Figure 6
ROC curves of RDW and TSH for the diagnostic abilities of revascularization in UA. AUC for RDW and TSH (blue lines), reference lines (red lines).
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Grants and funding

This research received no external funding. The publication costs of this article will be covered by the University of Zielona Góra.

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