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Review
. 2024 Feb 18;14(2):217.
doi: 10.3390/jpm14020217.

Microbiome Dynamics: A Paradigm Shift in Combatting Infectious Diseases

Mohamed Kamel  1 , Sami Aleya  2 , Majed Alsubih  3 , Lotfi Aleya  4
Affiliations
Review

Microbiome Dynamics: A Paradigm Shift in Combatting Infectious Diseases

Mohamed Kamel et al. J Pers Med. .

Abstract

Infectious diseases have long posed a significant threat to global health and require constant innovation in treatment approaches. However, recent groundbreaking research has shed light on a previously overlooked player in the pathogenesis of disease-the human microbiome. This review article addresses the intricate relationship between the microbiome and infectious diseases and unravels its role as a crucial mediator of host-pathogen interactions. We explore the remarkable potential of harnessing this dynamic ecosystem to develop innovative treatment strategies that could revolutionize the management of infectious diseases. By exploring the latest advances and emerging trends, this review aims to provide a new perspective on combating infectious diseases by targeting the microbiome.

Keywords: host–pathogen interactions; human microbiome; infectious diseases; microbiome-targeted therapies; treatment approaches.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Mechanisms of microbiome-mediated pathogenesis. The diagram depicts the intricate relationship between a host organism and its microbial companions, detailing how this interplay can result in disease-causing scenarios. It sheds light on various ways through which the microbiome can influence the development of infectious diseases.
Figure 2
Figure 2
Health benefits of the microbiome against infectious diseases. This figure illustrates the various ways in which the microbiome contributes to protecting the human body against infectious diseases.
Figure 3
Figure 3
Different approaches of microbiome-based therapies for infectious diseases. This figure illustrates various strategies and approaches for utilizing the microbiome as a therapeutic intervention in the treatment of infectious diseases.
See this image and copyright information in PMC

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