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. 2023 Nov 20;10(6):761-768.
doi: 10.14744/nci.2023.26037. eCollection 2023.

Risk factors and cost of nosocomial infections in pediatric patients with traumatic brain injury

Feyza Incekoy Girgian, Makbule Nilufer Ozturk

Risk factors and cost of nosocomial infections in pediatric patients with traumatic brain injury

Feyza Incekoy Girgian et al. North Clin Istanb. .

Abstract

Objective: This study aimed to determine the factors that increase nosocomial infections (NIs) in pediatric patients with traumatic brain injury (TBI) and the effects on both treatment cost and length of hospital stay.

Methods: We performed a case-control study on patients admitted to the pediatric intensive care unit (PICU) with (n=66) or without (n=120) TBI between 2012 and 2014. The risk factors, length of stay, and costs of NIs were determined.

Results: Data for 186 patients were analyzed. One hundred and twenty patients were controls (54 males vs. 66 females), while 66 were cases (27 males vs. 39 females). Seventeen out of the 186 PICU patients had NIs. About 7.6% of TBI patients had infections whereas 10% of control groups had NIs (p=0.58). The most isolated microbial agent was Acinetobacterbaumannii (four cases). Thirteen (76.5%) out of the 17 infections were catheter-related bloodstream infections. The mean expenses per PICU patient were $762, with an additional cost of $2081 for patients with nosocomial contamination.

Conclusion: The use of catheters was the most critical risk factor for NIs in our study probably underestimated the cost for several reasons. Nevertheless, the findings supported our hypothesis about the additional burden of nosocomial spread on PICU patients. This study's results should help provide evidence on cost-effectiveness or calculate the cost-benefit ratio of reducing NIs in children.

Keywords: Catheter-associated infections; cost; nosocomial infections; pediatric intensive care unit; traumatic brain injury.

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Conflict of interest statement

No conflict of interest was declared by the authors.

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Study flow chart.
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References

    1. Faul F, Erdfelder E, Lang AG, Buchner A. G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods. 2007;39:175–91. doi: 10.3758/BF03193146. - DOI - PubMed
    1. Hyder AA, Wunderlich CA, Puvanachandra P, Gururaj G, Kobusingye OC. The impact of traumatic brain injuries: a global perspective. Neuro Rehabilitation. 2007;22:341–53. doi: 10.3233/NRE-2007-22502. - DOI - PubMed
    1. Türkiye İstatistik Kurumu. İstatistiklerle Çocuk. 2017. Available at: https://data.tuik.gov.tr/Bulten/Index?p=Statistics-on-Child-2017-27596 Accessed Oct 13 2023. Turkish Statistics Institute [Child statistics]. https://www.tuseb.gov.tr/enstitu/tacese/yuklemeler/istatistik/istatistik....
    1. Gurskis V, Asembergiene J, Kefalas R, Miciuleviciene J, Pavilonis A, Valinteliene R, et al. Reduction of nosocomial infections and mortality attributable to nosocomial infections in pediatric intensive care units in Lithuania. Medicine (Kaunas) 2009;45:203–13. doi: 10.3390/medicina45030027. - DOI - PubMed
    1. Aydogdu S, Karamese M, Altoparlak U. Evaluation of the activities of antimicrobial agents on multi-drug resistant gram-positive bacteria isolated from intensive care units. SOJ Microbiol Infect Dis. 2014;2:1–5. - PubMed

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