Decoding Therapeutic Applications of Quercetin: Recent Advancements in Nanotechnological Strategies
- PMID: 38317469
- DOI: 10.2174/0122117385271262231114075737
Decoding Therapeutic Applications of Quercetin: Recent Advancements in Nanotechnological Strategies
Abstract
For centuries, people have used herbal medicine to treat a diversity of health complications and as a natural substance, they have a favourable effect on our health. Herbal ingredients can be utilized as lead molecules in the innovation and development of a new drug. Flavonoids are a class of chemical compounds with diverse phenolic structures, and they are found in a wide variety of foods, including fruits, vegetables, cereals, bark, roots, stems, flowers, tea, and wine. Quercetin is the most prevalent polyphenolic bioflavonoid or flavonoid. Quercetin is found in many food products and has demonstrated a wide range of pharmacological activities, including the treatment of allergies, ocular diseases, metabolic ailments, inflammatory illnesses, cardiovascular ailments and arthritis. Quercetin has attracted interest as an emerging pharmacophore with the potential to significantly advance research and the development of novel therapeutic medicines for a variety of diseases. Despite having a huge therapeutic potential, these flavonoids have unfavourable pharmacokinetic characteristics, low bioavailability, and poor solubility, limiting their application in therapeutics. The objective of the current study is to present a new update on the major therapeutic uses of quercetin and other types of nanocarriers that contain quercetin to treat various ailments.
Keywords: Quercetin; drug delivery; flavonols; nanomedicine; nanotechnology; natural compounds; therapeutic.
Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.
Similar articles
-
The Pharmacological Activity, Biochemical Properties, and Pharmacokinetics of the Major Natural Polyphenolic Flavonoid: Quercetin.Foods. 2020 Mar 23;9(3):374. doi: 10.3390/foods9030374. Foods. 2020. PMID: 32210182 Free PMC article. Review.
-
Flavonoids: A treasure house of prospective pharmacological potentials.Heliyon. 2024 Mar 9;10(6):e27533. doi: 10.1016/j.heliyon.2024.e27533. eCollection 2024 Mar 30. Heliyon. 2024. PMID: 38496846 Free PMC article. Review.
-
Quercetin as a Therapeutic Product: Evaluation of Its Pharmacological Action and Clinical Applications-A Review.Pharmaceuticals (Basel). 2023 Nov 20;16(11):1631. doi: 10.3390/ph16111631. Pharmaceuticals (Basel). 2023. PMID: 38004496 Free PMC article. Review.
-
[Research progress on therapeutic potential of quercetin].Zhongguo Zhong Yao Za Zhi. 2021 Oct;46(20):5185-5193. doi: 10.19540/j.cnki.cjcmm.20210524.602. Zhongguo Zhong Yao Za Zhi. 2021. PMID: 34738418 Chinese.
-
Nanotechnology Innovations to Enhance the Therapeutic Efficacy of Quercetin.Nanomaterials (Basel). 2021 Oct 9;11(10):2658. doi: 10.3390/nano11102658. Nanomaterials (Basel). 2021. PMID: 34685098 Free PMC article. Review.
Cited by
-
Combined Metabolomics and Transcriptomics Analysis of the Distribution of Flavonoids in the Fibrous Root and Taproot of Polygonatum kingianum Coll.et Hemsl.Genes (Basel). 2024 Jun 22;15(7):828. doi: 10.3390/genes15070828. Genes (Basel). 2024. PMID: 39062607 Free PMC article.
LinkOut - more resources
Full Text Sources