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Review
. 2024;17(1):16-30.
doi: 10.2174/0118746098241507231127114248.

Therapeutic Approaches to Increase the Survival Rate of Cancer Patients in the Younger and Older Population

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Review

Therapeutic Approaches to Increase the Survival Rate of Cancer Patients in the Younger and Older Population

Tharrun Paul et al. Curr Aging Sci. 2024.

Abstract

Various developments have been observed in the treatment of cancer patients, such as higher survival rates and better treatment outcomes. However, expecting similar outcomes in older patients remains a challenge. The main reason for this conclusion is the exclusion of older people from clinical trials for cancer drugs, as well as other factors, such as comorbidity, side effects, age-related frailties and their willingness to undergo multiple treatments. However, the discovery of new techniques and drug combinations has led to a significant improvement in the survival of the elderly population after the onset of the disease. On the other hand, cancer treatments have not become more complex for the younger population when compared to the older population, as the younger population tends to respond well to treatment trials and their physiological conditions are stable in response to treatments. In summary, this review correlates recent cancer treatment strategies and the corresponding responses and survival outcomes of older and younger patients.

Keywords: Cancer; ageing; cell therapy; chemotherapy; radiotherapy; survival rate..

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