Periarticular infiltration used in total joint replacements: an update and review article
- PMID: 37957753
- PMCID: PMC10641975
- DOI: 10.1186/s13018-023-04333-z
Periarticular infiltration used in total joint replacements: an update and review article
Abstract
Periarticular infiltration following total knee and hip arthroplasty has been demonstrated to be equivalent to peripheral nerve blocks for postoperative pain management. The ideal cocktail has not been established yet. We have conducted a literature search on PubMed and Embase. Our search criteria included randomized controlled trials (RCTs) and systematic reviews (SRs). We tried to only include the most recent studies to keep the information current. The included research focused at Dexmedetomidine, Liposomal Bupivacaine, Ropivacaine, Epinephrine, Ketorolac, Morphine, Ketamine and Glucocorticosteroids. Each medication's mode of action, duration, ideal dosage, contraindications, side effects and effectiveness have been summarized in the review article. This article will help the clinician to make an informed evidence-based decision about which medications to include in their ideal cocktail.
© 2023. Crown.
Conflict of interest statement
The authors declare no competing interests.
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References
-
- Zhao E, Zhou K, Liu Z, Ding Z, Lu H, Chen J, et al. Dexmedetomidine prolongs the analgesic effects of periarticular infiltration analgesia following total knee arthroplasty: a prospective, double-blind, randomized controlled trial. J Arthroplasty. 2023. - PubMed
-
- Nikhar SA, Yadav M, Damera S, Mohan L, Ch VJ, Ramachandran G. A Comparative study of periarticular infiltration with dexmedetomidine versus ketorolac as an additive to ropivacaine after total knee arthroplasty: a prospective, randomized double-blind study. Anesth Essays Res. 2020;14(4):550. doi: 10.4103/aer.AER_18_21. - DOI - PMC - PubMed
-
- Salem DAE, Nabi SMA, Alagamy SA, Kamel AAF. Comparative study between dexmedetomidine and fentanyl as an adjuvant to intraarticular bupivacaine for postoperative analgesia after knee arthroscopy. Pain Phys. 2021;24(7):E989. - PubMed
-
- Panigrahi R, Roy R, Mahapatra AK, Prasad A, Priyadarshi A, Palo N. Intra-articular adjuvant analgesics following knee arthroscopy: comparison between single and double dose dexmedetomidine and ropivacaine a multicenter prospective double-blind trial. Orthop Surg. 2015;7(3):250–5. doi: 10.1111/os.12182. - DOI - PMC - PubMed
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