Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Aug 6;11(22):5412-5415.
doi: 10.12998/wjcc.v11.i22.5412.

Caution in the use of sedation and endomyocardial biopsy for the management of pediatric acute heart failure caused by endocardial fibroelastosis

Xiao-Xuan Xin  1 , Yo-Yeng Se  2   3
Affiliations

Caution in the use of sedation and endomyocardial biopsy for the management of pediatric acute heart failure caused by endocardial fibroelastosis

Xiao-Xuan Xin et al. World J Clin Cases. .

Abstract

Endocardial fibroelastosis (EFE) is commonly considered to be an inflammatory reactive lesion of hyperplasia and deposition of tissue fibers and collagen in the endocardium and/or subendocardium, which is strongly associated with endocardial sclerosis, ventricular remodeling and acute and chronic heart failure, and is one of the important causes for pediatric heart transplantation. Early diagnosis and treatment are the key factors in determining the prognosis of the children. In this paper, we would like to highlight the potential unintended consequences of the use of sedation and biopsy for pediatric acute heart failure caused by EFE and the comprehensive considerations prior to clinical diagnosis.

Keywords: Comprehensive clinical diagnosis; Endocardial fibroelastosis; Endomyocardial biopsy; Sedation in children.

PubMed Disclaimer

Conflict of interest statement

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Figures

Figure 1
Figure 1
Prominent complications and contraindications of endomyocardial biopsy. EMB: Endomyocardial biopsy.
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Xie YY, Li QL, Li XL, Yang F. Pediatric acute heart failure caused by endocardial fibroelastosis mimicking dilated cardiomyopathy: A case report. World J Clin Cases. 2023;11:1771–1781. - PMC - PubMed
    1. Suzuki Y, Watanabe J, Ono S, Fukui N, Sugai T, Tsuneyama N, Someya T. Increase in the risk of chlorpromazine-induced QT prolongation during nighttime: is a short-period ECG during daytime sufficient? Prog Neuropsychopharmacol Biol Psychiatry. 2010;34:1122–1123. - PubMed
    1. Bradley BD, Green G, Ramsay T, Seely AJ. Impact of sedation and organ failure on continuous heart and respiratory rate variability monitoring in critically ill patients: a pilot study. Crit Care Med. 2013;41:433–444. - PubMed
    1. Qishuo T, Youyou Z, Jie Z, Yalei Y, Wei Z, Quan L, Liang L, Liang R. Role of the heat shock protein family in chlorpromazine-induced cardiotoxicity. J Appl Toxicol. 2023;43:1064–1072. - PubMed
    1. Brighenti M, Donti A, Giulia Gagliardi M, Maschietto N, Marini D, Lombardi M, Vairo U, Agnoletti G, Milanesi O, Pongiglione G, Bonvicini M Italian Society of Pediatric Cardiology. Endomyocardial biopsy safety and clinical yield in pediatric myocarditis: An Italian perspective. Catheter Cardiovasc Interv. 2016;87:762–767. - PubMed