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Review
. 2023 Jun 30;12(13):4431.
doi: 10.3390/jcm12134431.

Diagnosis and Non-Invasive Treatment of Obesity in Adults with Type 2 Diabetes Mellitus: A Review of Guidelines

Michał Łuniewski  1 , Beata Matyjaszek-Matuszek  1 , Monika Lenart-Lipińska  1
Affiliations
Review

Diagnosis and Non-Invasive Treatment of Obesity in Adults with Type 2 Diabetes Mellitus: A Review of Guidelines

Michał Łuniewski et al. J Clin Med. .

Abstract

Obesity, a chronic disease with multifactorial etiopathogenesis, is characterized by excessive accumulation of adipose tissue. Obesity prevalence is growing globally at an alarming rate. The overwhelming majority of obesity cases are caused by inappropriate lifestyles, such as overconsumption of food and inadequate physical activity. Metabolic and biochemical changes due to increased adiposity resulted in numerous comorbidities, increased all-cause mortality, and reduced quality of life. T2DM (type 2 diabetes mellitus) and obesity have many common pathogenetic points and drive each other in a vicious cycle. The aim of this article is to review obesity management guidelines and highlight the most important points. Management of both obesity-related and T2DM complications incur enormous expenses on healthcare systems. It is, therefore, paramount to provide streamlined yet custom-tailored weight management in order to avoid the negative ramifications of both diseases. Efficient obesity treatment leads to better diabetes control since some antidiabetic medications support weight reduction. Obesity treatment should be overseen by a multi-disciplinary team providing indispensable information and individually tailored regimens to patients. Weight management should be multimodal and consist chiefly of MNT (medical nutrition therapy), physical activity, and lifestyle changes. A comprehensive approach to obesity treatment may give tangible results to quality of life and comorbidities.

Keywords: GLP1-RA; SLGT2 inhibitor; medical nutrition therapy; weight management.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
The vicious cycle of obesity, insulin resistance, and diabetes type 2. IAPP (islet amyloid polypeptide). ↑ = an increase, ↓ = a decrease.
Figure 2
Figure 2
Overweight and obesity management algorithm (based on various recommendations) [20,21,81,95].
See this image and copyright information in PMC

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