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Editorial
. 2023 Jun 9;24(12):9932.
doi: 10.3390/ijms24129932.

Role of Telomeres and Telomerase in Cancer and Aging

Affiliations
Editorial

Role of Telomeres and Telomerase in Cancer and Aging

Gabriele Saretzki. Int J Mol Sci. .

Abstract

Seventeen papers published in 2019 and early 2020 demonstrate the ongoing interest and research concerning telomeres and telomerase in aging and cancer [...].

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Conflict of interest statement

The author declares no conflict of interest.

Figures

Figure 1
Figure 1
Overview of the 17 published papers and their main topics regarding telomeres and telomerase/TERT in aging and cancer. TL: telomere length, ESC: embryonal stem cells.

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References

    1. Chang W.-F., Wu Y.-H., Xu J., Sung L.-Y. Compromised Chondrocyte Differentiation Capacity in TERC Knockout Mouse Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer. Int. J. Mol. Sci. 2019;20:1236. doi: 10.3390/ijms20051236. - DOI - PMC - PubMed
    1. Le Berre G., Hossard V., Riou J.-F., Guieysse-Peugeot A.-L. Repression of TERRA Expression by Subtelomeric DNA Methylation Is Dependent on NRF1 Binding. Int. J. Mol. Sci. 2019;20:2791. doi: 10.3390/ijms20112791. - DOI - PMC - PubMed
    1. Azzalin C.M., Lingner J. Telomere functions grounding on TERRA firma. Trends Cell Biol. 2015;25:29–36. doi: 10.1016/j.tcb.2014.08.007. - DOI - PubMed
    1. Yuan X., Xu D. Telomerase Reverse Transcriptase (TERT) in Action: Cross-Talking with Epigenetics. Int. J. Mol. Sci. 2019;20:3338. doi: 10.3390/ijms20133338. - DOI - PMC - PubMed
    1. Yu J., Yuan X., Sjoholm L., Liu T., Kong F., Ekstrom T.J., Bjorkholm M., Xu D. Telomerase reverse transcriptase regulates DNMT3B expression/aberrant DNA methylation phenotype and AKT activation in hepatocellular carcinoma. Cancer Lett. 2018;434:33–41. doi: 10.1016/j.canlet.2018.07.013. - DOI - PubMed

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