Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Sep-Oct;54(5):379-380.
doi: 10.4103/ijp.ijp_899_21.

LD50 dose fixation of nanohybrid-layered double hydroxide-methotrexate

Affiliations

LD50 dose fixation of nanohybrid-layered double hydroxide-methotrexate

Akhilesh Mishra et al. Indian J Pharmacol. 2022 Sep-Oct.
No abstract available

PubMed Disclaimer

Conflict of interest statement

None

Figures

Figure 1
Figure 1
Graphical method of determination of LD50 of LDH-MTX formulation in rats. LDH-MTX = Layered double hydroxides-methotrexate

Similar articles

References

    1. Sperling F. Introduction to toxicity evaluation session. Environ Health Perspect. 1979;32:259. - PMC - PubMed
    1. Chinedu E, Arome D, Ameh FS. A new method for determining acute toxicity in animal models. Toxicol Int. 2013;20:224–6. - PMC - PubMed
    1. Gaies E, Jebabli N, Trabelsi S, Salouage I, Charfi R, Lakhal M, et al. Methotrexate side effects. J Drug Metab Toxicol. 2012;3:125.
    1. Choi G, Kwon OJ, Oh Y, Yun CO, Choy JH. Inorganic nanovehicle targets tumor in an orthotopic breast cancer model. Sci Rep. 2014;4:4430. - PMC - PubMed
    1. Chakraborty M, Dasgupta S, Bose P, Mishra A, Mandal TK, Mitra M, et al. Layered double hydroxide: Inorganic organic conjugate nanocarrier for methotrexate. J Phys Chem Solids. 2011;72:779–83.